Study #3010: Impact of protein and alkali supplementation on skeletal muscle in older adults

For more information about enrolling in this study, please call:

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Target population:
Individuals, ages 65 years and older

Purpose of this study:
To examine the independent and additive effects of whey protein supplementation and potassium bicarbonate (KHCO3) supplement on changes in measures of lower extremity muscle power

Major Exclusions:        

  • Age <65
  • Medications and supplements:
    • Oral steroids for > 10 days in last 3 months
    • Oral, injectable, or topical anabolic and gonadal hormones in the last 6 months
    • Potassium containing supplements or products
    • Insulin
    • Sulfonylureas
  • Conditions/ Diseases:
    • A kidney stone in the last 5 years
    • Kidney disease
    • Crohn’s disease
    • Active malignancy or cancer therapy in the last year
    • Use of a wheelchair or walker

Length of study:

  • 24 weeks


  • None


  • $25 for screening visit and up to $1000 for participants who qualify and complete entire study

Number of visits:

  • 1 screening visit; up to 8 intra-study visits    

Study diet:

  • Maintain usual diet during the study; add a whey protein (or placebo powder packet) and potassium bicarbonate (KHCO3) supplement (or placebo) to each meal

Can I work?:

  • Yes, but not on the mornings of the baseline (visit 2), 12 week (visit 5) and final 24 week (visit 8).